KPSC-MOCK-TEST Mock Exam

KPSC Mock Test: Assistant Professor in Pharmacology - Medical Education Department

Official Kerala Public Service Commission ONLINE Exam Question Paper & Answer Key. • Name of Post: Assistant Professor in Pharmacology - Medical Education Department • Question Paper Code: 28/2024/OL- • Answer Key: Final Answer Key Question Paper PDF: https://www.keralapsc.gov.in/sites/default/files/2024-03/pharmacology.pdf Answer Key PDF: https://www.keralapsc.gov.in/sites/default/files/2024-04/Final%20Answer%20key-%20Asst%20Professor%20in%20Pharmacology.pdf

100 Questions

Progress: 0 / 100 Answered

Which of the following is an example for supra additive synergism?

All are examples of pharmacogenetically mediated adverse effects except

All the following molecules act through JAK/STAT receptors except

Which of the following drugs produce phototoxicity? i. Amiodarone ii. Sulfonamides iii. Phenothiazines iv. Phenytoin

Characteristic features of intramuscular route of drug administration i. Hypertonic solution can be injected ii. Only water solutions can be injected iii. Oily solutions can be injected

Which of the following statements are correct about Meta-analysis? i. Cannot prove cause and effect ii. Evaluation and grouping of similar studies iii. Aim is to decrease the number of subjects studied

Which statement is not true about transdermal therapeutic system?

Among the following combinations which is not a CYP3A4 substrate and its inhibitor?

All are indications of therapeutic drug monitoring except

Which of the following statements are correct about clinical trial? i. Phase I - Dose range, safety and tolerability, only in patients ii. Phase II - Therapeutic efficacy and dose range in patients iii. Phase III - Drug safety and tolerability in large number of patients iv. Phase IV - Therapeutic efficacy in large number of patients

Systemic clearance of a drug is directly related with all the following except

Which statement is not true about OATP1B1 transporter?

Which schedule under the drugs and cosmetics rules, 1945 deals with the prescription of tramadol and pentazocine?

Among the following benzodiazepines which is preferred in elderly individuals?

Quality Adjusted Life Years (QALYS) is a measure of which pharmacoeconomic analysis

Botulinum toxin is beneficial in all except

Among the following drugs which is not useful in acute congestive glaucoma

All are advantages of third generation

\beta

blocker Nebivolol except

All are properties of halothane except

Which adverse effect is more seen with pentazocin than with morphine?

All are AMPA blockers used as antiepileptic drugs except

Which of the following statement is not true about Agomelatine an atypical antidepressant drug?

All are adverse effects of clozapine which is an atypical antipsycholic agent except

Baclofen is a centrally acting skeletal muscle relaxant used to treat following clinical conditions except

All are properties of local anesthetic agent Ropivacaine i. Short acting ii. Less cardiotoxicity iii. Blocks A

\delta

and C fibres completely iv. Used epidurally for labour pain

Which among the following beta blocker has the longest half life?

Longest acting

5-HT_{1D/1B}

agonist is

Which of the following calcium channel blockers can delay the progression of early stages of type I diabetes by improving the survival of pancreatic beta cells?

Choose the drug which attenuates platelet aggregation by antagonising thromboxane receptor :

In patients with diabetes and chronic kidney disease which of the following drugs can reduce heart failure events and renal function decline

The following antiarrhythmic drug produces anticholinergic side effects

Which of the following drug is the first line therapy for severe Pulmonary Artery Hypertension (Functional Class IV)

Idarucizumab is a reversal agent for toxicity due to

Which of the following antiplatelet drug has rapid onset of action and a circulating half life of 3 to 4 days?

Evolocumab is a

Thrombopoietin Receptor Agonist (TRAs) preferred in chronic hepatitis C virus (HCV) associated thrombocytopenia

GnRH agonist which can be given intranasally is

Which of the following statement regarding methimazole is correct

Hypoactive Sexual Desire Disorder (HSDD) is treated with :

Phosphodiesterase 5 (PDE5) inhibitor with maximum duration of action is

Anti inflammatory potency is maximum for

Inoperable adrenocortical carcinoma is treated with

Which of the following insulin preparation forms multihexameric complexes after sub cutaneous injection?

The GLP-1 agonist approved for weight loss independent of diabetes status are i. Dulaglutide ii. Liraglutide iii. Lixisenatide iv. Semaglutide

The following bisphosphonate is preferred in treatment of hypercalcemia because of its more rapid normalization of serum and longer duration of action

The Vitamin D analogue used in the treatment of Psoriasis is

Diagnostic testing of cancer specimen for BRAF V 600 mutation is important in guiding treatment decision for the following drug

Most neurotoxic alkylating agent is

Which of the following drug is a very potent radiosensitizer and should not be used with radiotherapy?

Pancreatic Neuro Endocrine Tumor is treated with

Abiraterone is used for the treatment of

Bedaquiline acts by

Guanosine analogue with antiretroviral action is

Orally effective antifungal antibiotic capable of inducing microsomal enzymes is

An orange dye which exerts analgesic action in urinary tract is

Advantages of Artemisinin based combination therapy include all except

All are true about Linezolid EXCEPT

Minocycline, in comparison to Doxycycline,

The antimicrobial agent effective against pseudomonas is

Topically effective sulphonamide preparation for bacterial conjunctivities is

Orally effective carbapenem, resistant to inactivation by renal dehydropeptidase is

The mismatched pair among the following is

All are uses of N Acetyl Cysteine except

The CCK1/CCKA receptor antagonist that increases motility of the gastrointestinal tract is

New formula for WHO-ORS provides

Emesis is induced by

Active form of the Enkephalinase inhibitor, Racecadotril is

In Rheumatoid arthritis, Anakinra acts by

Alprostadil effective in Erectile dysfunction in males is a

The true statement about probenecid is

Orally effective drug in scabies is

Drug effective in treatment of Vitiligo is

Nephrotoxicity is less common with the use of

Immunostimulant action is exhibited by

Lowering of intraocular pressure is seen with the use of

Dimercaprol is contraindicated in

Povidone lodine is an example for

Find the wrong pair

Read the assertion and reason statements and choose the single best response Assertion (A) : Sildenafil causes impaired blue green discrimination Reason (R): Sildenafil is a weak inhibitor of phosphodiesterase 6

False statement about lorcaserin is

Experimental animal commonly used for pyrogen testing

According to prevention of Cruelty to Animals Act 1960, definition of 'animal' includes all except

Sodium dihydrogen phosphate is a constituent of

Which of the anesthetic agents is not suitable for the study of cardiovascular drugs in experimental animals

Which among the following can be used as a mobile phase in normal phase HPLC?

Which among the following is not used as a label in Radioimmunoassay

Mean total cholesterol values of 50 diabetic patients is 346 mg/dl with standard deviation of 20 and that of non-diabetics is 288 mg/dl with standard deviation 9. To compare these values, which statistical test is the most appropriate?

According to the empirical rule, approximately what percentage of the date should lie within +/-2SD

If the data are normally distributed with a mean of 180 and standard deviation of 40. Between what two values will approximately 68% of the data fall

In a box and whisker plot, two sides of the box represent

Bradykinin receptor antagonist useful for symptomatic treatment of hereditary angioedema

An endocrine disrupting chemical is

The preferred drug in type 2 diabetes mellitus patient with patient with cardiac failure

Which among the following is not an example of drug repurposing?

Which among the statements regarding Semaglutide is incorrect?

The drug useful for controlling delusions, hallucinations and psychosis in parkinson's disease

Which among the following is not included in world Health Organisation's prescribing indicators

Which among the following is a Watch drug as per Aware classification of antimicrobials?

The partial nicotine receptor agonist useful in smoking cessation

100

The assumed average maintenance dose per day for a drug used for its main indication in adults is

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